In this type of cutaneous lupus, the skin lesions are round (disk-shaped), thick, scaly and red
) Withdrawal of the culprit agent often leads to resolution of the skin disease
Subacute cutaneous lupus erythematosus (SCLE) is one type of cutaneous lupus
, namely: acute cutaneous lupus, subacute cutaneous lupus, and chronic cutaneous lupus erythematosus
Environmental factors INTRODUCTION — Discoid lupus erythematosus (DLE) and subacute cutaneous lupus erythematosus (SCLE) are variants of cutaneous lupus erythematosus (cutaneous LE) that may occur independently or as manifestations of systemic lupus erythematosus (SLE)
7% and 30
Most side effects will go away when your body gets used to the medicine
Be sure to talk to your rheumatologist if you have any other questions or concerns
Abstract The antimalarial hydroxychloroquine (HCQ) has demonstrated several crucial properties for the treatment of systemic lupus erythematosus (SLE)
Now, new research underscores the importance of long-term HCQ maintenance for many people
In the mid-1940s, both hydroxychloroquine (HCQ) and chloroquine (CQ) had been synthesized
Background and Objectives: Cutaneous lupus erythematosus (CLE) presents clinically heterogeneous manifestations, partially explained by the different expression of Toll-like receptors (TLRs) type 8 and 9, located to endosomal compartments where they are poised to recognize microbial nucleic acids
As in idiopathic or usual-type lupus erythematosus (LE), there are three categories recognised: Drug-induced systemic LE (SLE) Drug Subacute cutaneous lupus (SCLE) usually involves rashes on sun-exposed areas
Abstract
Subacute Cutaneous Lupus Erythematosus (SCLE) About 10% of lupus patients have SCLE
They can look like a ring with a darker red circle on the ring's outer edge
Cutaneous manifestations may occur as a single separate entity of the disease (cutaneous lupus erythematosus, CLE) or in association with systemic involvement of multiple organs, such as Subacute cutaneous lupus erythematosus (SCLE) is an autoimmune disease that may be induced by proton pump inhibitors (PPIs) in at-risk populations
10%-15% of patients go on to have systemic findings
SCLE presents clinically with erythematous annular or papulosquamous cutaneous eruptions in sun-exposed areas []
1 Prompt diagnosis of CLE requires a thorough understanding of the cutaneous manifestations and clinical spectrum of lupus
A treatment plan for cutaneous lupus may include one or more of the following medications: A corticosteroid: Cutaneous (skin) lupus often responds quickly to a corticosteroid
Long-term use of hydroxychloroquine (HCQ) can cause areas of increased skin pigmentation (typically bluish-black)
INTRODUCTION
diagnosis of atypical subacute CLE with positive anti-Ro(SS-A) and anti-La(SS-B) serology
Acute cutaneous lupus: Known for a "butterfly rash" that looks like a sunburn across your cheeks and nose
The diagnosis is challenged by the variation in time from prescription of the culprit drug to the appearance of SCLE
Sam Lim discussed what Cutaneous examination showed multiple well-defined erythematous to hypopigmented scaly papules and plaques [Figure 1a] on the sites, as mentioned earlier
Other antimalarials, like chloroquine, are rarely used these days and may cause more side effects
This drug is commonly used to manage multiple complications of lupus and other connective tissue disorders
It is part of a group of auto-immune skin disorders known as 'cutaneous lupus erythematosus (CLE)'
Methods We devised a set of diagnostic criteria for SCLE in collaboration Cutaneous lupus erythematosus (CLE) is a disfiguring and potentially disabling disease that causes significant morbidity in patients
They were treated by HCQ (5 mg/Kg/qd) and Qn with two Subacute cutaneous lupus erythematosus (SCLE) is a clinically distinct disease that is associated with systemic lupus erythematosus in 50% of patients, and can be associated with Sjögren's syndrome and patients with a deficiency in the second and fourth components of complement
Subacute cutaneous lupus is a rash with red, ring-shaped sores or scaly patches with distinct edges
Doctors use antimalarials to treat malaria, but these medicines can also treat lupus by: Reducing pain and inflammation
Lupus that only affects the skin is less common and is called cutaneous lupus erythematosus (CLE)
Learn about the wide-ranging effects of hydroxychloroquine (Plaquenil®) in the treatment of lupus: dosing, benefits, side effects and rare complications of this commonly prescribed medication
Hydroxychloroquine is widely used for the treatment of cutaneous lupus erythematosus (CLE)
CCLE encompasses discoid lupus erythematosus (DLE), lupus
Effective in treating
Cutaneous lupus erythematosus (CLE) encompasses several clinical entities ranging from discoid lupus erythematosus (DLE) to subacute cutaneous lupus
The US FDA does not recognize SCLE as an adverse event associated with PPIs
9% and 81
Herein, we reviewed the main HCQ pharmacologic features, detailed its mechanism of action, and summarized the existing guidelines and recommendations for HCQ use in rheumatology
1 Prompt diagnosis of CLE requires a thorough understanding of the cutaneous
Medication: Dermatologists prescribe medications to treat a lupus rash and other skin problems, help regrow hair, and alleviate symptoms like pain
The rash commonly occurs on the back, chest, and arms but sometimes extends to the buttocks
, 2
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Antimalarial drugs, such as hydroxychloroquine (Plaquenil®), fight fatigue, reduce rashes and decrease joint pain
Subacute cutaneous lupus erythematosus (SCLE) may be induced or aggravated by drugs
The first video is a panel presentation on the impact of COVID-19 on people with lupus and an overview of COVID-19 vaccines
Other mucocutaneous, general, and systemic examinations were within normal limits